International Journal of Research and Review

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Original Research Article

Year: 2017 | Month: May | Volume: 4 | Issue: 5 | Pages: 96-99

Prevalence of Hemoglobinopathies in Antenatal Screening by HPLC

Dr. Urshlla Kaul1*, Dr. Reeta Dhar2*, Dr. Nitin Kadam3**, Dr. Smriti Dewan4**, Dr. Apoorva Misra4**, Dr. Vibhuti Maru5**

1Resident, 2Professor and HOD, 3Director, 4Pathologist, 5Clinical Biochemist,
*Dept of Pathology, MGM Medical College, Kamothe
**MGM Hospital, Vashi, Mumbai

Corresponding Author: Dr. Urshlla Kaul


We studied a total of 234 married, pregnant females coming for routine antenatal screening for presence or absence of Hemoglobinopathies over a period of one year in a tertiary level hospital. The prevalence was found to be 5.1% (12 cases). Out of these 7(2.9%) females had beta thalassemia trait and 5(2.1%) were having variant hemoglobin of which 3(1.28%) females were Hb E Heterozygous, 1(0.4%) was Hb D Punjab and 1(0.4%) was Hb Q India. Such screening for Hemoglobinopathies should be conducted as they prove to be important for the health of the mother and the child as well as spreading awareness, further screening of family members (spouses, siblings) to prevent birth of homozygous babies.

Key words: Hemoglobinopathies, HPLC, Antenatal screening

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