IJRR

International Journal of Research and Review

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Review Article

Year: 2017 | Month: February | Volume: 4 | Issue: 2 | Pages: 37-46

Vitamin D and Its Implications in Various Diseases

Shubhangi Sharma1, Shikhaa Mahajan2, Suvarna Prasad3, Neeru Bhaskar4,  Sunita Manhas2, Ritu  Devi1

1MSc. Medical Student, 2Assistant Professor, 3Professor & Head, 4Professor,
Department of Biochemistry, MMIMSR, Maharishi Markandeshwar University, Ambala.

Corresponding Author: Shubhangi Sharma

ABSTRACT

Vitamin D is not just a vitamin and functions mainly as hormone. The functional form of vitamin D i.e. calcitriol functions through gene modulation and through extra genetical mechanisms through vitamin D receptors on the cell surface (VDR). There are various epidemiological as well as clinical data describing the beneficial role of vitamin D in the osteoporosis, cancer, immunity, diabetes, multiple sclerosis and rheumatoid arthritis. The main action of vitamin D is mediated through cell cycle regulation and modulation of the immune system.

Key words: Vitamin D, Calcitriol, disease, diabetes, biochemical basis.

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