Original Research Article
Year: 2015 | Month: December | Volume: 2 | Issue: 12 | Pages: 711-713
Assessment of Oral Glucose Tolerance in Women Attending Ante Natal in Some Private Clinics in Port Harcourt: A Measure of Gestational Diabetes
Anacletus F.C, Okoroafor N. A.
Department of Biochemistry, Faculty of Science, University of Port Harcourt, Port Harcourt, Rivers state, Nigeria.Corresponding Author: Anacletus F.C
A prevalence study of Oral Glucose Tolerance was performed in 69 women attending ante-natal clinic in various private hospitals in Port Harcourt. After an overnight fast of about 8 – 12 hours, a venous blood sample was taken for fasting blood sugar level before a 75g glucose load was given. Blood samples were taken at 30 minute intervals for a period of 2 hours, after which their blood glucose concentration was investigated using Glucose Oxidase Method. The results obtained showed that there was a percentage deviation of 17.4% under the Fasting Blood Sugar test and 20.3 % after the 2-hours post prandial. The incidence of Gestational Diabetes Mellitus from the results according to World Health Organization (WHO) criteria was present in 5.8% of the total population(FBS - ≥ 7.0 mmol/l and 2-hr post prandial - ≥ 11.1 mmol/l) and Impaired Glucose Tolerance(IGT) was present in 24.6% (FBS - 5.6 - 7.0 mmol/l and 2-hr post prandial - 7.8-11.1mmol/l). Also, 7.25% were impaired in both FBS and IGT at the same time. 1.4% had impaired fasting plasma blood sugar and outright diabetes after 2-hours post prandial. Assessment of gestational diabetes through OGTT is mandatory because it is the only test that determines glucose intolerance in asymptomatic people so that glycaemic control can be achieved as to avoid long-term implications on both mother and child.
Key words: Gestational Diabetes, Oral Glucose Tolerance Test, Impaired glucose Tolerance.